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Mannitol is not reabsorbed in the renal tubules, maintains a high osmotic pressure in the lumen of the tubules, and retains water throughout the nephron tubular apparatus.
The diuretic effect is much more pronounced and is characterized by the release of a large amount of water, as well as sodium ions. With intravenous (slow jet or drip) administration, the effect develops after 10-15 minutes and after 1 hour the drug is excreted.
Apply it to cause forced diuresis in acute poisoning (barbiturates, salicylates), acute renal failure, as well as acute heart failure in patients with reduced renal filtration. It has a dehydrating effect, due to the ability to increase the osmotic pressure of blood plasma. For the purpose of dehydration, it is prescribed Buy Cenmox (Amoxicillin) intravenously 250mg, 500mg online - Antibiotics, with cerebral edema and severe attacks of glaucoma, since the drug does not penetrate biological membranes. In addition, it is used for oliguria associated with Buy Amoxil (Amoxicillin) 250mg, 500mg, 650mg, 1000mg, 625mg online - Antibiotics injuries, burns and large blood loss. Hypersensitivity to the components of the drug, hereditary fructose intolerance, a history 250mg, 500mg (Amoxicillin) Buy - Antibiotics Cenmox online of successful anti-alcohol treatment or alcoholism.
Tablets should not be taken by patients with hereditary galactose intolerance, lactase deficiency or malabsorption of glucose-galactose.
Overdose The goal of therapy in this phase should be the activation of detoxification mechanisms.
High fever should not be suppressed by allopathic antipyretic drugs, which can cause progressive vicariation. In this phase, it is recommended to prescribe Traumeel S, Galium-Heel, Hepar compositum, Phosphor-Homaccord, Engystol (for viral infections) and Echinacea compositum (for bacterial infections).
In the acute period of the disease, it is recommended to start treatment with parenteral administration of the drug.
After the end of the course of infusion therapy, it is recommended to continue treatment orally at a dose of 1-2 tablets (5-10 mg) 3 times a day
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) has a complex of different and at the same time complementary pharmacological effects.
By inhibiting phosphodiesterase, it increases the concentration of cAMP in vascular smooth muscle. At the same time, vascular tone decreases, blood flow improves in the ischemia zone and the peri-infarction zone, the rheological properties of blood, metabolism in the brain tissue and transmembrane transport of glucose are normalized. Under its influence, the affinity of erythrocytes for blood oxygen increases, as well as their ability to transfer oxygen to tissues, the elasticity of the wall of red blood cells increases, and the reabsorption of adenosine into erythrocytes is inhibited. Of the side effects, a transient decrease in blood pressure and tachycardia are observed. - a combined drug, the neuroprotective effect of which lies in the selective stimulation of the metabolism of the brain, in the stabilization of the cerebral and systemic circulation, slowing down the death of brain neuron cells. The drug moderately expands the coronary and cerebral vessels, increases the utilization of glucose and oxygen by brain cells. When using the drug, working capacity increases, fatigue, headache decrease, mood and general tone increase. If arrhythmia occurs, 2–2.4 g of potassium chloride is injected intravenously with 10 IU of insulin in 500 ml of 5% glucose solution. Means that contain potassium are contraindicated in violation of atrioventricular conduction. With severe bradycardia, a solution of atropine sulfate is prescribed. Unithiol, ethylenediaminetetraacetate are also prescribed as a detoxifying agent. At development paraplegia shown surgical skye decompression.
MDS Gauze napkins, folded in 4–5 layer- ev, moisten solution and apply on the eye- gi defeat on the 20–30 min daily in flow 3 weeks. Overdose Main representatives: spironolactone, triamterene. Triamterene acts in the distal tubules and in the cortical collecting ducts. It causes a moderate pharmacological effect, but, unlike other diuretics, does not cause potassium loss.
It reduces the permeability of the membranes of the distal tubules for sodium, chlorine, increases the excretion of uric acid and retains potassium.